Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders.
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Human psychopharmacology and dose-effects of salvinorin A, a kappa opioid agonist hallucinogen present in the plant Salvia divinorum. Drug Alcohol Depend. Salvia divinorum: Effects and use among YouTube users. National Institute on Drug Abuse for Teens. Your Privacy Rights. To change or withdraw your consent choices for VerywellMind. At any time, you can update your settings through the "EU Privacy" link at the bottom of any page. These choices will be signaled globally to our partners and will not affect browsing data.
We and our partners process data to: Actively scan device characteristics for identification. I Accept Show Purposes. Table of Contents View All. Table of Contents. What Does Salvia Do?
Common Side Effects. Signs of Use. Addiction and Withdrawal. How to Get Help. How to Recognize Salvia Salvia has large, spade-shaped green leaves that look similar to mint. Was this page helpful? Thanks for your feedback! Sign Up. What are your concerns? Pipes or water bongs may be used to smoke these extracts. The salvia extracts may also be infused in drinks or vaporizer pens.
Fresh salvia leaves can be chewed, too. That means possible side effects and risks that could be detrimental to your health may not be understood yet. How much salvia is safe to ingest depends on what type of salvia you use. Salvia is potent, so small doses may produce hallucinogenic effects. If you use extracts, less is more.
The NDIC recommends that the higher the extract concentration, the smaller the dose. For example, 0. If you try 10x salvia extract, a safe range may be between 0. How salvinorin A, the active ingredient in salvia, impacts your brain is unclear.
Researchers continue to study the drug to better understand its effects. Salvia studies are few and far between, but researchers are looking to better understand how the drug works and what effects it may have on the body and brain. Because research is limited, the list of possible side effects and risks is short. However, the possible issues are serious and worth consideration. Salvia largely flew under the radar until when a video of pop music star Miley Cyrus made waves on the internet.
In the video, the thenyear-old singer and actress was filmed smoking salvia in a water bong. The video brought the spotlight of attention to this drug, and some state legislators began introducing laws restricting the sale and use of this plant.
Salvia is illegal in a number of foreign countries and in many American states. Possession or use of salvia in states where it is illegal is punishable by fines and jail time. Reviewed by: Steven Dowshen, MD. Larger text size Large text size Regular text size.
What It Is: Salvia is an herb that's native to the mountains of southern Mexico. Sometimes Called: diviner's sage, magic mint, maria pastora, sally-d, seer's sage, and shepherdess's herb How It's Used: As a drug, salvia usually comes as fresh green plant leaves or dried shredded green leaves. What It Does: Salvia's effects come on quickly, sometimes in less than a minute. Common short-term effects include: hallucinations and changes in visual perception uncontrolled laughter mood and emotional swings difficulty concentrating a sense of detachment from self and reality not being able to tell the difference between what's real and what's imagined dizziness and lightheadedness lack of coordination slurred speech Some studies suggest that, over time, salvia use may contribute to a condition called dysphoria that is characterized by feelings of depression, discontent, and restlessness.
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